Histologic variants of FSGS and clinical outcomes

FSGS collaping variant has the poorest outcome

A prospective study by D'Agati et al. show that there is correlation between histologic variants of FSGS and clinical data including demography, clinical presentation and outcome.

Some notes:

• The study is part of a controlled trial for FSGS treatment
• This is the first prospective study regarding histologic variant of FSGS
• Only 138 patients enrolled results in too few patients in cellular and perihilar variants to be analyzed
• The patients' age is <40 year old and all are steroid resistant before enrollment