Renal prognosis a long time after renal biopsy on patients with diabetic nephropathy

Kimmelstiel-Wilson nodule characteristic of class III lesion

Mise et al. retrospectively studied correlation between histologic parameters and renal
survival in patients with diabetic nephropathy. They found that histologic classification (Tervaert's), tubular atrophy/interstitial fibrosis and arterial lesions correlated with renal survival.
This is the first validation study of diabetic nephropathy histologic classification in which its association with renal outcome was shown.